Personally I would not care if they never played Run to the Hills live ever again, and I could easily do without The Number of the Beast as well.
They're classics. That's why they play them. The problem is with TV/radio overplay and the fact that they're arguably the most famous Maiden songs so are generally used first as examples in any conversation involving metal. That kind of over-exposure just makes you take the songs for granted.
Trust me, if they hadn't have played those two tracks last night, the rumblings of discontent from Donington would have been heard down at the Ruskin Arms.
If you just don't like the songs, however, then that's just down to personal taste and that's perfectly fine. Musical opinion has no right or wrong answer.
But you'd be wrong.